{"id":6900,"date":"2026-11-02T19:00:55","date_gmt":"2026-11-02T19:00:55","guid":{"rendered":"https:\/\/globalnigerianews.com\/index.php\/2026\/11\/02\/africas-first-ever-phase-1-trial-of-a-long-acting-injectable-for-malaria-prevention-launches-in-rwanda-businessday-ng\/"},"modified":"2026-11-02T19:00:55","modified_gmt":"2026-11-02T19:00:55","slug":"africas-first-ever-phase-1-trial-of-a-long-acting-injectable-for-malaria-prevention-launches-in-rwanda-businessday-ng","status":"publish","type":"post","link":"https:\/\/globalnigerianews.com\/index.php\/2026\/11\/02\/africas-first-ever-phase-1-trial-of-a-long-acting-injectable-for-malaria-prevention-launches-in-rwanda-businessday-ng\/","title":{"rendered":"Africa\u2019s first-ever Phase 1 trial of a long-acting injectable for malaria prevention launches in Rwanda \u2013 Businessday NG"},"content":{"rendered":"

Medicines for Malaria Venture (MMV)
and Rinda Ubuzima, a leading Rwandan health research organization, today announced the launch of\u00a0 a Phase 1b clinical trial for a potential long-acting injectable (LAI) for malaria prevention.\n<\/p>\n

The study marks a critical step in the development of the compound known as MMV371 and is the first Phase 1
trial of a malaria LAI to be conducted in Africa.\n<\/p>\n

Provided that they prove to be safe and effective, LAIs could become an important addition to the malaria
prevention toolbox, complementing existing interventions such as vector control measures, vaccines and preventive medicines.\n<\/p>\n

Why new tools are needed\n<\/p>\n

Despite significant progress against malaria since the turn of the century, the disease remains a major public health challenge: according to the World Health Organization, in 2024, malaria caused over 280 million cases and 600,000 deaths, 95 percent of which occurred in Africa.<\/p>\n

The continued emergence of antimalarial drug resistance, changing disease patterns driven by climate change-related extreme weather events and fragile health systems highlight the need for sustained investment in R&D and
continued innovation, coupled with greater access to malaria prevention and treatment tools.\n<\/p>\n

Given these challenges, MMV is working with partners to develop the first LAI designed to provide extended protection against malaria.\n<\/p>\n

The Phase 1b study builds on earlier clinical research conducted in the United Kingdom, which found that MMV371 was well tolerated in healthy adults and showed the potential to provide protection for approximately 3 months.\n<\/p>\n

This next phase will evaluate its safety and tolerability in Rwandan adults and adolescents, explore its efficacy, and understand how the body absorbs and processes the compound.\n<\/p>\n

\u201cTo eliminate malaria, we will need not only wider access to today\u2019s tools but also the next generation of prevention technologies,\u201d said Dr Martin Fitchet, Chief Executive Officer of MMV. \u201cLong-acting injectables have the potential to redefine how malaria prevention is delivered, providing sustained
protection from a single administration and expanding the options available to communities at risk.\u201d<\/p>\n

Partnerships for malaria elimination
Partnerships are critical to the development of new malaria interventions. MMV has a strong track record of working with partners across industry, government and academia to bring new medicines to those who need them.\n<\/p>\n

The collaboration with Rinda Ubuzima builds on this approach, reflecting a shared commitment to advancing innovation through locally led research, while strengthening scientific research capacity and generating the evidence needed to develop the next generation of malaria tools.\n<\/p>\n

\u201cConducting this study in Rwanda demonstrates that partnerships such as this are essential to ensuring
that African researchers and institutions are active contributors to the development of solutions for the
communities and countries that need them most,\u201d said Marie Michele Umulisa, Executive Director of Rinda Ubuzima.\n<\/p>\n

\u201cWe are proud to contribute to research that could help shape the future of malaria prevention while strengthening locally led scientific innovation.\u201d\n<\/p>\n

As countries work towards ending malaria, collaborative efforts such as this clinical trial are helping to
pave the way for new preventive approaches and expand the range of tools available to protect at-risk
communities.<\/p>\n

The study also reflects a broader shift towards conducting increasingly sophisticated early-stage
clinical research in malaria-endemic countries and ensuring that the development of medicines is
informed by the communities they are intended to serve earlier in the R&D process.<\/p>\n

\n\t\t\t\t\t\t\"\"\t\t\t\t\t\t<\/p>\n
\n\t\t\t\t\t\t\tIfeoma Okeke-Korieocha<\/a><\/strong><\/p>\n

Ifeoma Okeke-Korieocha is the Aviation Correspondent at BusinessDay Media Limited, publishers of BusinessDay Newspapers.
\n
\nShe is also the Deputy Editor, BusinessDay Weekender Magazine, the Saturday Weekend edition of BusinessDay.
\n
\nShe holds a BSC in Mass Communication from the prestigious University of Nigeria, Nsukka and a Masters degree in Marketing at the University of Lagos.
\n
\nAs the lead writer on the aviation desk, Ifeoma is responsible and in charge of the three weekly aviation and travel pages in BusinessDay and BDSunday. She also overseas and edits all pages of BusinessDay Saturday Weekender.
\n
\nShe has written various investigative, features and news stories in aviation and business related issues and has been severally nominated for award in the category of Aviation Writer of the Year by the Nigeria Media Nite-Out awards; one of the Nigeria\u2019s most prestigious media awards ceremonies.
\n
\nIfeoma is a one-time winner of the
\nprestigious Nigeria Media Merit Award under the ‘Aviation Writer of the Year’ Category.
\n
\nShe is the 2025 Eloy Award winner under the Print Media Journalist category.
\n
\nShe has undergone several journalism trainings by various prestigious organisations.
\n
\nIfeoma is also a fellow of the Female Reporters Leadership Fellowship of the Wole Soyinka Centre for Investigative Journalism.<\/p>\n<\/p><\/div>\n<\/p><\/div>\n

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Source: <\/p>\n

Businessday NG<\/div>\n","protected":false},"excerpt":{"rendered":"

Medicines for Malaria Venture (MMV)and Rinda Ubuzima, a leading Rwandan health research organization, today announced the launch of\u00a0 a Phase 1b clinical trial for a potential long-acting injectable (LAI) for… <\/p>\n","protected":false},"author":1,"featured_media":6901,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-6900","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-business"],"_links":{"self":[{"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/posts\/6900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/comments?post=6900"}],"version-history":[{"count":0,"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/posts\/6900\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/media\/6901"}],"wp:attachment":[{"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/media?parent=6900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/categories?post=6900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/globalnigerianews.com\/index.php\/wp-json\/wp\/v2\/tags?post=6900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}